Skip to content

What are the different types of HRT?

Two trans friends sit on bench and talk to one another

Hormone replacement therapy (HRT) can be an important part of gender-affirming care for many trans and non-binary individuals. The medications used in hormone replacement therapy vary depending on whether you are seeking masculinizing or feminizing hormone therapy. Here are some of the different types of hormone replacement therapy medications and delivery methods:

Feminizing hormone therapy

  1. Estrogen therapy: Estrogen is the primary hormone used in feminizing hormone therapy. It can be delivered through pills, patches, injections, or sublingual tablets. Dosages and frequency of administration vary depending on the individual and their specific needs.

  2. Anti-androgen therapy: Anti-androgens are sometimes used in combination with estrogen to block the effects of testosterone. Common anti-androgens include spironolactone, cyproterone acetate, and finasteride. These medications are usually taken orally.

Masculinizing hormone therapy

  1. Testosterone therapy: Testosterone is the primary hormone used in masculinizing hormone therapy. It can be delivered through injections, patches, gels, or pellets. Dosages and frequency of administration vary depending on the individual and their specific needs.

  2. Aromatase inhibitors: Aromatase inhibitors are sometimes used in combination with testosterone to prevent the conversion of testosterone to estrogen. Common aromatase inhibitors include anastrozole and letrozole. These medications are usually taken orally.

Summary

Hormone replacement therapy for transgender and non-binary individuals is highly individualized and must be tailored to the individual's specific needs and goals. The dosages and frequency of administration may vary depending on the individual's response to treatment and any potential side effects.

It is important to work with a knowledgeable and experienced healthcare provider to determine the most appropriate hormone replacement therapy regimen for your transition.

If you need help accessing HRT you cannot afford or easily/safely obtain, learn more about Point of Pride's HRT Access Fund.